Elliott J R, Haydon D A
Biochim Biophys Acta. 1984 Jun 13;773(1):165-8. doi: 10.1016/0005-2736(84)90561-3.
The electrical capacities per unit area of planar lipid bilayers formed from monoolein/n-hexadecane, monoolein/ squalane (or squalene) and monoolein/triolein have been measured in the presence of a range of n-alkanols. For monoolein/n-hexadecane bilayers, the effects of the n-alkanols are complicated but can be rationalized in terms of the likely changes in lipid chain order and the influence of the n-alkanol in the Plateau-Gibbs border. Monoolein/ squalane (or squalene) and monoolein/triolein bilayers exhibit behaviour quite different from the n-hexadecane membranes. For both the squalane and triolein bilayers the shorter chain alkanols increase the capacity per unit area while the longer homologues have little effect. These results help to account for the influence of the n-alkanols on gramicidin single-channel lifetimes.
