Wheeler S L, Pool G L, Lumb R H
Biochim Biophys Acta. 1984 Jul 6;794(2):348-9. doi: 10.1016/0005-2760(84)90166-8.
Otitis media results when the eustachian tube fails to adequately ventilate the middle ear. A surface tension-lowering substance may be required for normal tube opening, especially in young children with poorly developed naso-pharyngeal musculature. We report here that rat eustachian tube epithelium synthesizes disaturated phosphatidylcholine, which is recognized as the surface tension-lowering substance of pulmonary surfactant.
当中耳咽鼓管不能充分使中耳通气时，就会引发中耳炎。正常的咽鼓管开放可能需要一种能降低表面张力的物质，尤其是在鼻咽部肌肉组织发育不良的幼儿中。我们在此报告，大鼠咽鼓管上皮会合成二饱和磷脂酰胆碱，它被认为是肺表面活性物质中降低表面张力的物质。
