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5-(2-溴-E-乙烯基)-2'-脱氧尿苷的血浆代谢物鉴定。

Identification of a plasma metabolite of 5-(2-bromo-E-ethenyl)-2'-deoxyuridine.

作者信息

Robinson Y, Gerry N, Brownsill R D, Vose C W

出版信息

Biomed Mass Spectrom. 1984 Apr;11(4):199-201. doi: 10.1002/bms.1200110412.

Abstract

A prominent plasma metabolite was detected in animals and man after oral administration of 5-(2-bromo-E- ethenyl )-2'-deoxyuridine. The metabolite was isolated by solvent extraction and high-performance liquid chromatography and was identified by mass spectrometry as 5-(2-bromo-E- ethenyl )uracil.

摘要

在动物和人体口服5-(2-溴-E-乙烯基)-2'-脱氧尿苷后检测到一种显著的血浆代谢物。该代谢物通过溶剂萃取和高效液相色谱法分离,并通过质谱鉴定为5-(2-溴-E-乙烯基)尿嘧啶。

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