Rabins P V, Merchant A, Nestadt G
Br J Psychiatry. 1984 May;144:488-92. doi: 10.1192/bjp.144.5.488.
Eighteen patients fulfilling DSM-III criteria for both major depression and dementia were matched by age and sex to patients with a diagnosis of irreversible dementia and patients with a diagnosis of major depression. A past history of depression, self reports of depressed mood, self blaming, hopeless and somatic delusions, an appetite disturbance and subacute onset identified the patients suffering from dementia caused by depression. Two year follow-up confirmed the initial diagnosis and demonstrated that coexisting cognitive impairment and major depression are not usually precursory to a progressive dementing illness.
18名符合DSM-III标准的重度抑郁症和痴呆症患者，按年龄和性别与诊断为不可逆性痴呆症的患者以及诊断为重度抑郁症的患者进行匹配。有抑郁症病史、情绪低落的自我报告、自责、绝望和躯体妄想、食欲紊乱以及亚急性起病可确定患有抑郁所致痴呆症的患者。两年的随访证实了最初的诊断，并表明共存的认知障碍和重度抑郁症通常不是进行性痴呆疾病的先兆。
