Ernst C, Angst J
Psychiatric University Hospital, Zürich, Switzerland.
Eur Arch Psychiatry Clin Neurosci. 1995;245(6):272-87. doi: 10.1007/BF02191869.
The discrepancy between the constancy or increase of the prevalence of depressive symptoms and dysphoria in old age on one hand, and the decrease in the prevalence of the DSM-III diagnoses of major depression and dysthymia on the other, is discussed in light of the most frequent explanatory hypotheses such as memory defects, interpretation of depressive as somatic symptoms, higher risk of institutionalization as well as higher mortality of depressives and a mitigated course of depression in old age. We conclude that higher mortality, mitigation and the rarity of true late-onset depression are arguments for a real decline in prevalence, which occurs in accordance with the decline in all psychiatric disorders that are connected with emotional upheavals and substance ingestion. On the other hand, the connection of depressive states with somatic illness is strengthened, and according to preliminary validation studies, clinically relevant depressive states not reaching the threshold of DSM-III diagnoses may be typical for the depressive psychopathology of old age.
一方面是老年期抑郁症状和烦躁不安的患病率持续或上升,另一方面是重度抑郁症和心境恶劣的DSM-III诊断患病率下降,针对这一差异,我们根据最常见的解释性假设进行了讨论,这些假设包括记忆缺陷、将抑郁解释为躯体症状、住院风险较高以及抑郁症患者死亡率较高和老年期抑郁症病程减轻等。我们得出结论,较高的死亡率、病情减轻以及真正晚发性抑郁症的罕见性表明患病率确实下降,这与所有与情绪剧烈波动和物质摄入相关的精神疾病患病率下降相一致。另一方面,抑郁状态与躯体疾病的联系得到加强,并且根据初步验证研究,未达到DSM-III诊断阈值但具有临床相关性的抑郁状态可能是老年期抑郁心理病理学的典型表现。