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健康成年人血清IgG亚类浓度:一项使用单克隆抗血清的研究。

Serum IgG subclass concentrations in healthy adults: a study using monoclonal antisera.

作者信息

French M A, Harrison G

出版信息

Clin Exp Immunol. 1984 May;56(2):473-5.

Abstract

IgG subclass concentrations have been measured in the sera of 172 healthy adults using monoclonal antisera. 'Normal ranges' are given. The findings were similar to those of previous studies of European populations but differed from the findings of the only other study of a large British population. In particular, low proportions of IgG4 in a British population have not been confirmed. IgG4 concentrations were higher in males than females (P = less than 0.00003) and IgG3 concentrations were higher in females than males (P = 0.034).

摘要

已使用单克隆抗血清对172名健康成年人的血清进行了IgG亚类浓度测定,并给出了“正常范围”。研究结果与先前针对欧洲人群的研究相似,但与另一项针对大量英国人群的研究结果不同。特别是,英国人群中IgG4比例较低这一发现未得到证实。男性的IgG4浓度高于女性(P<0.00003),女性的IgG3浓度高于男性(P = 0.034)。

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