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有儿童哮喘病史的年轻成年人的特应性体质及对吸入乙酰胆碱的支气管反应性

Atopic disposition and bronchial reactivity to inhaled acetylcholine in young adults with a history of asthma in childhood.

作者信息

Nagata S, Ago Y, Teshima H, Imada Y

出版信息

J Asthma. 1984;21(3):151-9. doi: 10.3109/02770908409077414.

DOI:10.3109/02770908409077414
PMID:6735972
Abstract

The atopic disposition, indicated by positive skin reactions and IgE antibody titers etc., and the bronchial reactivity to inhaled acetylcholine were examined on the following three groups: (1) 20 young adults with a history of childhood asthma who have been symptom-free for more than 4 yr; (2) 20 current asthmatics, and (3) 20 healthy young adults. Young adults with a history of childhood asthma remained atopic in their disposition even after complete clinical remissions of their childhood asthma. However, they had a lower bronchial reactivity as compared with current asthmatics, although the bronchial reactivities of both groups were apparently higher than the control group.

摘要

通过皮肤阳性反应和IgE抗体滴度等指标表明的特应性体质,以及对吸入乙酰胆碱的支气管反应性,在以下三组人群中进行了检测:(1)20名有儿童哮喘病史且已无症状超过4年的年轻成年人;(2)20名现患哮喘者;(3)20名健康年轻成年人。有儿童哮喘病史的年轻成年人即使在儿童哮喘完全临床缓解后,其体质仍保持特应性。然而,与现患哮喘者相比,他们的支气管反应性较低,尽管两组的支气管反应性均明显高于对照组。

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J Asthma. 1984;21(3):151-9. doi: 10.3109/02770908409077414.
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