Habig W H, Jakoby W B, Guthenberg C, Mannervik B, Vander Jagt D L
J Biol Chem. 1984 Jun 25;259(12):7409-10.
2-Propylthiouracil has been reported as replacing glutathione as a substrate for the glutathione transferases of rat liver. This observation has been examined with several homogeneous glutathione transferases that were prepared from human and rat liver by different methods in three laboratories. No evidence was obtained for 2-propylthiouracil as a substrate for glutathione transferase in the several reactions tested.
据报道，2-丙基硫氧嘧啶可取代谷胱甘肽作为大鼠肝脏谷胱甘肽转移酶的底物。三个实验室通过不同方法从人和大鼠肝脏中制备了几种均一的谷胱甘肽转移酶，并对这一观察结果进行了研究。在所测试的几个反应中，未获得2-丙基硫氧嘧啶作为谷胱甘肽转移酶底物的证据。
