Misiewicz A
Med Pr. 1984;35(1):21-7.
Studies involved 69 men occupationally exposed--on average for 9-4 years--to manganese dusts and vapours at 0.00013 mg/l-0.00449 mg/l concentrations and trace amounts of ferrum and titanium. The control group consisted of 41 men unexposed to toxic substances. Those chronically exposed to manganese exhibited changes in serum albumins immunoelectrophoretic picture in form of much weaker saturation of IgA and IgM arches, transferrin and ceruloplasmin, and markedly increased saturation of IgG arches. Those changes may result from toxic effects of manganese upon liver cells.
研究涉及69名职业暴露的男性，他们平均在9至4年的时间里暴露于浓度为0.00013毫克/升至0.00449毫克/升的锰粉尘和蒸汽中，以及微量的铁和钛。对照组由41名未接触有毒物质的男性组成。长期接触锰的人血清白蛋白免疫电泳图谱出现变化，表现为IgA和IgM弧、转铁蛋白和铜蓝蛋白的饱和度明显降低，而IgG弧的饱和度显著增加。这些变化可能是锰对肝细胞产生毒性作用的结果。
