Punnonen R, Vilska S, Rauramo L
Maturitas. 1984 Apr;5(4):259-62. doi: 10.1016/0378-5122(84)90019-7.
Skinfold thickness was measured in 130 post-menopausal women treated with long-term hormone therapy. One group of 50 women took oestradiol valerate 2 mg/day for 3 wk out of 7, a second group comprising 19 women received oestriol succinate 2 mg/day and the remaining group of 61 women used oestradiol valerate 2 mg/day combined sequentially with norgestrel 0.5 mg/day. The duration of treatment in these groups was 6.3 +/- 0.4, 6.4 +/- 0.4 and 3.3 +/- 0.3 yr, respectively. The control group was made up of a further 89 post-menopausal women. The skinfold thickness in all the treated groups was significantly greater than that in the controls.
对130名接受长期激素治疗的绝经后女性进行了皮褶厚度测量。一组50名女性，在7周中有3周每天服用2毫克戊酸雌二醇；第二组19名女性，每天服用2毫克琥珀酸雌三醇；其余61名女性则每天联合服用2毫克戊酸雌二醇和0.5毫克炔诺酮，采用序贯疗法。这些组别的治疗时长分别为6.3±0.4年、6.4±0.4年和3.3±0.3年。对照组由另外89名绝经后女性组成。所有治疗组的皮褶厚度均显著高于对照组。
