Ferbus D, Justesen J, Bertrand H, Thang M N
Mol Cell Biochem. 1984 Apr;62(1):51-55. doi: 10.1007/BF00230077.
The (2'-5') oligoadenylate synthetase normally found in interferon-treated cells has also been detected in considerable amounts in normal rabbit reticulocytes not exposed to interferon. The activity of this enzyme has been followed during the development of the reticulocytes to erythrocytes. A high level was found just after the formation of reticulocytes and this activity decayed with a half-life of about 3 days. In lymphocytes the (2'-5') oligoadenylate synthetase was found to stay at a constant level, which indicates the absence of interferon in the plasma.
通常在经干扰素处理的细胞中发现的（2'-5'）寡腺苷酸合成酶，在未接触干扰素的正常兔网织红细胞中也大量检测到。在网织红细胞发育为红细胞的过程中，对这种酶的活性进行了跟踪。在网织红细胞形成后立即发现其活性水平很高，且这种活性以约3天的半衰期衰减。在淋巴细胞中，发现（2'-5'）寡腺苷酸合成酶保持恒定水平，这表明血浆中不存在干扰素。
