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[在给未受照射和局部受照射动物施用维生素B3活性化合物期间肝脏中乙酰化辅酶硫醇形式含量的变化]

[Changes in the content of the thiol form of the acetylation coenzyme in the liver during administration of vitamin B3-active compounds to intact and locally irradiated animals].

作者信息

Rozanov V A

出版信息

Radiobiologiia. 1984 May-Jun;24(3):353-5.

PMID:6739738
Abstract

A local exposure of mouse head to gamma-rays caused phase changes in CoASH content of the liver. The administration of D-pantothenate-Ca and D-pantethine increased the level of CoASH in the liver of exposed animals; calcium D-homopantothenate did not influence the co-enzyme content. It is suggested that pantothenate and pantethine act like vitamins while the influence of homopantothenate is associated with the effects of calcium ions.

摘要

小鼠头部局部暴露于γ射线会导致肝脏中辅酶A(CoASH)含量发生相变。给予D-泛酸钙和D-泛硫乙胺可提高受照射动物肝脏中CoASH的水平;D-高泛酸钙对辅酶含量没有影响。有人认为,泛酸和泛硫乙胺的作用类似于维生素,而高泛酸钙的影响与钙离子的作用有关。

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