Stiksa G
Schweiz Med Wochenschr. 1984 May 12;114(19):642-8.
In the light of substantial recent advances in knowledge regarding the use of inhaled corticosteroids, general recommendations for such treatment are reviewed. The therapeutic effect is dose-related. High dose treatment has been shown to be effective in improving asthma control and reducing oral steroid requirement, while adverse side effects are usually of little consequence. The use of metered dose inhalers using correct technique and at a convenient time is a basic prerequisite in securing maximum effect. The development of new drugs with a better separation of local and systemic effects is improving therapeutic potential.
鉴于近期在吸入性糖皮质激素使用方面的知识取得了重大进展,现对这种治疗的一般建议进行综述。治疗效果与剂量相关。高剂量治疗已被证明在改善哮喘控制和减少口服类固醇需求方面有效,而不良副作用通常影响不大。使用定量吸入器并采用正确技术且在方便的时间使用是确保获得最大效果的基本前提。具有更好的局部和全身效应分离效果的新药的研发正在提高治疗潜力。