Hesdorffer C, Derman D P, Bezwoda W R
S Afr Med J. 1984 Jul 14;66(2):54-6.
Measurement of pleural fluid and blood carcinoembryonic antigen (CEA) concentrations as well as estimations of pleural fluid protein, lactic acid dehydrogenase and sugar levels were carried out in 45 patients with pleural effusions in order to determine the value of these biochemical parameters in the diagnosis of malignant tumours involving the pleural space. The study population included individuals with epithelial and non-epithelial malignant tumours involving the pleural cavity as well as patients with inflammatory effusions and patients with transudates due to cardiac, renal or hepatic disease. Pleural fluid CEA content was the single most useful measurement in distinguishing epithelial malignant tumours from other causes of pleural effusion. In addition, the pleural fluid CEA/blood CEA ratio was greater than 1 in most patients with epithelial cancer of the pleural space, suggesting that local production of CEA is responsible for elevated values in the pleural fluid.
对45例胸腔积液患者进行了胸水和血液癌胚抗原（CEA）浓度的测定，以及胸水蛋白质、乳酸脱氢酶和糖水平的评估，以确定这些生化参数在诊断累及胸腔的恶性肿瘤中的价值。研究人群包括患有累及胸膜腔的上皮性和非上皮性恶性肿瘤的个体，以及炎性胸腔积液患者和因心脏、肾脏或肝脏疾病导致的漏出液患者。胸水CEA含量是鉴别上皮性恶性肿瘤与其他胸腔积液原因的最有用的单一检测指标。此外，大多数胸膜腔上皮癌患者的胸水CEA/血液CEA比值大于1，这表明胸水CEA值升高是由局部产生的CEA所致。
