Ogino M, Koike K, Satoh K, Arai K
Gan To Kagaku Ryoho. 1984 Sep;11(9):1770-4.
Pleural effusion is an important and common clinical finding. Pleural effusions can be readily obtained for analysis, and the examination of the cells therein is considered to be one of the most important diagnostic tools available for differentiating between malignant and non-malignant effusions. The present study was undertaken to test the diagnostic value of the determination of CEA in pleural fluid for a variety of diseases. Sixteen patients with pleural effusions were studied. Seven patients had carcinoma of the cervix, 7 of the ovary and 2 of the corpus. The positive rate of malignant cells was 81%. Among malignant effusions, only 44% of patients showed a CEA value above 10 mg/ml. This investigation suggests that cytological examination of pleural fluid is of considerable clinical significance for diagnosing the nature of pleural effusions, and effusion fluid CEA assay may provide a useful adjunct in the evaluation of effusion fluids for malignancy.
胸腔积液是一项重要且常见的临床发现。胸腔积液易于获取用于分析，对其中细胞的检查被认为是区分恶性和非恶性积液最重要的诊断工具之一。本研究旨在测试测定胸腔积液中癌胚抗原（CEA）对多种疾病的诊断价值。对16例胸腔积液患者进行了研究。其中7例患有宫颈癌，7例患有卵巢癌，2例患有子宫体癌。恶性细胞的阳性率为81%。在恶性积液中，仅有44%的患者癌胚抗原值高于10mg/ml。本调查表明，胸腔积液的细胞学检查对于诊断胸腔积液的性质具有相当大的临床意义，而积液中癌胚抗原检测在评估积液是否为恶性方面可能是一项有用的辅助手段。
