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[长期运动负荷和固定后大鼠皮肤弹性纤维的变化]

[Changes in the elastic fibers of the skin in rats after long-term motor loading and immobilization].

作者信息

Cheresharov L, Konstantinov N

出版信息

Vet Med Nauki. 1984;21(3):86-90.

PMID:6740926
Abstract

The histologic changes were followed up that took place in the elastic fibers of the skin of a total of 30 female rats of the Wistar line at the initial age of 45 days. The animals were kept under the conditions of enhanced or lowered locomotor activity. It was found that as functional elements in the particular layers of the skin the elastic fibers altered considerably their specific morphologic characteristic under the effect of a varying loading the body with muscular activity. The skin of those of the animals that were loaded with enhanced locomotion presented a strongly developed hyperplastic net of elastic fibers of considerable thickness and density. On the other hand, the skin of the animals that were immobilized showed atrophic and reduction processes involving the elastic tissue; in such case the characteristic structure and network arrangement were only presented by sporadic fibres and bundles. The changes seen in the structure and organization of the elastic tissue once again demonstrated the importance of the higher or lower functional loading of the body with physical work for the development of hyper- or hypotrophic processes in the various tissues and organs.

摘要

对45日龄初始阶段的30只Wistar系雌性大鼠皮肤弹性纤维的组织学变化进行了跟踪研究。这些动物分别饲养在运动活性增强或降低的条件下。结果发现,作为皮肤特定层中的功能元件,弹性纤维在身体因肌肉活动而承受不同负荷的影响下,其特定形态特征发生了显著变化。运动活性增强的动物的皮肤呈现出厚度和密度可观的高度发达的弹性纤维增生网络。另一方面,被固定的动物的皮肤显示出弹性组织的萎缩和退化过程;在这种情况下,特征性结构和网络排列仅由散在的纤维和纤维束呈现。弹性组织结构和组织的变化再次证明了身体因体力活动而承受的功能负荷高低对于各种组织和器官中增生或萎缩过程发展的重要性。

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