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[大鼠小肠吸收上皮细胞在运动活性增强和制动期间的超微结构变化]

[Ultrastructural changes in the resorptive epithelial cells of the small intestine in rats during increased motor activity and immobilization].

作者信息

Cheresharov L, Toshkova S, Bozhkov S, Lazarov I

出版信息

Vet Med Nauki. 1982;19(6):65-75.

PMID:7157653
Abstract

Investigated were the structural changes in the epithelial resorptive cells of the duodenum and the jejunum of rats in the conditions of continuous and varying locomotor activity--intense locomotion, control, and immobilization. It was established that the microvilli in the immobilized animals were of a lower size, were irregularly distributed and lower in number. The inward bending of the lateral cell boundary was more slightly manifested. Disaggregations of the polysomes were also expressed. In rats loaded with higher locomotion activity there was more frequently a close association of the mitochondria with the granular endoplasmatic reticulum and the nucleus. The changes observed spoke of lowering of the active cell surface and lowering of the biosynthesis rate in the epithelial resorptive cells at immobilization and enhanced metabolic activity in locomotor loading.

摘要

研究了在持续和变化的运动活动条件下——剧烈运动、对照和固定,大鼠十二指肠和空肠上皮吸收细胞的结构变化。结果发现,固定动物的微绒毛尺寸较小,分布不规则且数量较少。细胞外侧边界的向内弯曲表现得更轻微。多核糖体的解体也有表现。在运动活动较高的大鼠中,线粒体与颗粒内质网和细胞核之间的紧密联系更为频繁。观察到的变化表明,固定时上皮吸收细胞的活性细胞表面降低,生物合成率降低,而运动负荷时代谢活性增强。

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