[Activity of several membrane-bound creatine kinase isoenzymes in the rabbit myocardium in experimental disruption of coronary circulation].

Activity of CPK isoenzymes, bound with membranes of mitochondria and sarcoplasmic reticulum, was decreased under conditions of acute limitation of rabbit coronary circulation followed by intravenous administration of vasopressin at a dose of 0.5 un per kg of body mass. As a result of this phenomenon the efficient energy-dependent transport of calcium across the membranes of sarcoplasmic reticulum might be impaired with the subsequent development of complex alterations in functional and metabolic parameters, which are found in ischemic myocardium.