Frol'kis R A, Voronkov G S
Ukr Biokhim Zh (1978). 1987 Nov-Dec;59(6):70-2.
Acute myocardial ischemia (intravenous 0.2 U/kg vasopressin infusion) is shown to cause various changes in the creatine kinase isoenzyme activity: it decreases in mitochondria and sarcoplasmic reticulum and increases in myofibrils and cytosol, no significant alterations taking place in sarcolemma. It may be suggested that the stated changes are important components of the complex adaptational reactions which occur in the ischemic myocardium and support its main contractional function.
急性心肌缺血(静脉输注0.2 U/kg血管加压素)可导致肌酸激酶同工酶活性发生多种变化:线粒体和肌浆网中的活性降低,肌原纤维和胞质溶胶中的活性增加,而肌膜中未发生明显改变。可以认为,上述变化是缺血心肌中发生的复杂适应性反应的重要组成部分,有助于维持其主要收缩功能。