French J H, Thomas R G, Siskind A P, Brodsky M, Iseri L T
Ann Emerg Med. 1984 Jul;13(7):562-6. doi: 10.1016/s0196-0644(84)80534-x.
A potentially fatal case of massive digitalis intoxication is presented. Recurrent ventricular fibrillation failed to respond to lidocaine or phenytoin, but responded dramatically to magnesium sulfate infusion. A review of the literature and previous clinical studies, as well as the case reported here, appears to indicate that magnesium sulfate given intravenously in adequate quantities (2 to 3 g in one minute followed by 2 g/h for 4 to 5 h) is effective in controlling ventricular irritability caused by toxic levels of digitalis preparations.
本文报告了一例可能致命的大量洋地黄中毒病例。反复出现的室性颤动对利多卡因或苯妥英钠无反应，但对静脉输注硫酸镁有显著反应。对文献和既往临床研究以及本文报道的病例进行回顾后发现，静脉给予足量硫酸镁（1分钟内给予2至3克，随后4至5小时内每小时给予2克）可有效控制洋地黄制剂中毒水平所致的心室激惹。
