Mody G M, Naidoo P D
Ann Rheum Dis. 1984 Jun;43(3):394-7. doi: 10.1136/ard.43.3.394.
A retrospective study was carried out to determine the frequency, age of onset, mode of presentation, pattern of joint involvement, and incidence of primary and secondary gout in black patients with gout who were admitted to the King Edward VIII Hospital in Durban, South Africa. Nineteen patients were admitted to hospital with gout over a 5-year period from 1977 to 1981. The admission rate was found to be 4.7/100 000 hospital admissions. Five patients (26%) presented with monoarthritis and 14 patients (74%) had polyarthritis on admission. The joints most frequently involved were the knees (74%), the first metatarsophalangeal (MTP) joint (58%), and ankles (42%). The serum uric acid (SUA) was increased in 94%, and tophi were noted clinically in 47%. Eight patients (42%) with hypertension were on treatment with diuretics and 7 of these patients had a raised blood urea. These 8 patients (42%) were considered to have secondary gout, while no secondary causes were noted in the remaining 11 patients (58%) who had primary gout.
开展了一项回顾性研究，以确定南非德班爱德华八世国王医院收治的痛风黑人患者中痛风的发病率、发病年龄、临床表现方式、关节受累模式以及原发性和继发性痛风的发生率。在1977年至1981年的5年期间，有19名痛风患者入院。发现入院率为4.7/10万次住院。5名患者（26%）表现为单关节炎，14名患者（74%）入院时患有多关节炎。最常受累的关节是膝关节（74%）、第一跖趾关节（58%）和踝关节（42%）。94%的患者血清尿酸（SUA）升高，47%的患者临床上可见痛风石。8名（42%）高血压患者正在接受利尿剂治疗，其中7名患者血尿素升高。这8名患者（42%）被认为患有继发性痛风，而其余11名（58%）患有原发性痛风的患者未发现继发性病因。
