• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一名获得性免疫缺陷综合征患者的进行性多灶性白质脑病

Progressive multifocal leukoencephalopathy in a patient with acquired immune deficiency syndrome.

作者信息

Bernick C, Gregorios J B

出版信息

Arch Neurol. 1984 Jul;41(7):780-2. doi: 10.1001/archneur.1984.04050180102028.

DOI:10.1001/archneur.1984.04050180102028
PMID:6743070
Abstract

Progressive multifocal leukoencephalopathy (PML) occurred in a heterosexual Haitian man with acquired immune deficiency syndrome (AIDS). The patient initially had focal neurologic signs and nonenhancing lesions on a computed tomographic scan. Although PML is rare, it should be included in the differential diagnosis of opportunistic infections associated with AIDS. Brain biopsy is suggested in patients suspected of having PML who might benefit from antiviral therapy.

摘要

进行性多灶性白质脑病(PML)发生在一名患有获得性免疫缺陷综合征(AIDS)的海地异性恋男性身上。患者最初有局灶性神经体征,计算机断层扫描显示有非强化性病变。尽管PML很少见,但在与AIDS相关的机会性感染的鉴别诊断中应考虑到它。对于怀疑患有PML且可能从抗病毒治疗中获益的患者,建议进行脑活检。

相似文献

1
Progressive multifocal leukoencephalopathy in a patient with acquired immune deficiency syndrome.一名获得性免疫缺陷综合征患者的进行性多灶性白质脑病
Arch Neurol. 1984 Jul;41(7):780-2. doi: 10.1001/archneur.1984.04050180102028.
2
Progressive multifocal leukoencephalopathy in a child with acquired immunodeficiency syndrome (AIDS).一名患有获得性免疫缺陷综合征(艾滋病)的儿童发生进行性多灶性白质脑病。
Arq Neuropsiquiatr. 1997 Mar;55(1):122-5. doi: 10.1590/s0004-282x1997000100019.
3
Progressive multifocal leukoencephalopathy with gray matter involvement.伴灰质受累的进行性多灶性白质脑病
Can J Neurol Sci. 1989 May;16(2):200-2. doi: 10.1017/s0317167100028912.
4
[Progressive multifocal leukoencephalopathy as initial manifestation of acquired immunodeficiency].[进行性多灶性白质脑病作为获得性免疫缺陷的初始表现]
Rev Soc Bras Med Trop. 1998 Nov-Dec;31(6):569-74.
5
Progressive multifocal leukoencephalopathy in AIDS: a clinicopathologic study and review of the literature.艾滋病相关的进行性多灶性白质脑病:一项临床病理研究及文献综述
J Neurol. 1993 Jul;240(7):391-406. doi: 10.1007/BF00867351.
6
Progressive multifocal leukoencephalopathy occurring with the acquired immune deficiency syndrome.获得性免疫缺陷综合征相关的进行性多灶性白质脑病
South Med J. 1984 Aug;77(8):1041-3. doi: 10.1097/00007611-198408000-00028.
7
[The inefficacy of zidovudine (AZT) in progressive multifocal leukoencephalopathy (PML) associated with the acquired immunodeficiency syndrome (AIDS)].
Rev Clin Esp. 1990 Nov;187(8):404-7.
8
Progressive multifocal leukoencephalopathy in a case of acquired immune deficiency syndrome.获得性免疫缺陷综合征患者的进行性多灶性白质脑病
Clin Neurol Neurosurg. 1985;87(1):27-33. doi: 10.1016/0303-8467(85)90062-9.
9
[Progressive multifocal leukoencephalopathy in a patient with acquired immunodeficiency syndrome].
Rev Med Chil. 1993 Sep;121(9):1032-6.
10
Progressive multifocal leukoencephalopathy (PML) in two cases of cortical blindness.两例皮质盲患者发生进行性多灶性白质脑病(PML)。
AIDS Patient Care. 1994 Jun;8(3):110-3. doi: 10.1089/apc.1994.8.110.

引用本文的文献

1
Teriflunomide Inhibits JCPyV Infection and Spread in Glial Cells and Choroid Plexus Epithelial Cells.特立氟胺抑制神经胶质瘤细胞和脉络丛上皮细胞中的 JCPyV 感染和扩散。
Int J Mol Sci. 2021 Sep 10;22(18):9809. doi: 10.3390/ijms22189809.
2
Use of check-point inhibitors in the treatment of progressive multifocal leukoencephalopathy.检查点抑制剂在进行性多灶性白质脑病治疗中的应用。
Ann Transl Med. 2019 Dec;7(Suppl 8):S297. doi: 10.21037/atm.2019.11.11.
3
Progressive Multifocal Leukoencephalopathy and Monoclonal Antibodies: A Review.进行性多灶性白质脑病与单克隆抗体:综述
Cancer Control. 2017 Oct-Dec;24(4):1073274817729901. doi: 10.1177/1073274817729901.
4
Progressive multifocal leukoencephalopathy in multiple sclerosis.多发性硬化症中的进行性多灶性脑白质病。
Curr Neurol Neurosci Rep. 2013 Dec;13(12):408. doi: 10.1007/s11910-013-0408-6.
5
Progressive multifocal leukoencephalopathy and newer biological agents.进行性多灶性白质脑病与新型生物制剂。
Drug Saf. 2010 Nov 1;33(11):969-83. doi: 10.2165/11537510-000000000-00000.
6
Monoclonal antibodies and progressive multifocal leukoencephalopathy.单克隆抗体与进行性多灶性白质脑病。
MAbs. 2009 Nov-Dec;1(6):583-9. doi: 10.4161/mabs.1.6.9884.
7
Natalizumab and progressive multifocal leucoencephalopathy.那他珠单抗与进行性多灶性白质脑病
Ann Rheum Dis. 2006 Nov;65 Suppl 3(Suppl 3):iii48-53. doi: 10.1136/ard.2006.058404.
8
Progressive multifocal leukoencephalopathy in acquired immunodeficiency syndrome: explaining the high incidence and disproportionate frequency of the illness relative to other immunosuppressive conditions.获得性免疫缺陷综合征中的进行性多灶性白质脑病:解释该疾病相对于其他免疫抑制状况的高发病率和不成比例的发病频率。
J Neurovirol. 2003;9 Suppl 1:38-41. doi: 10.1080/13550280390195261.
9
Progressive multifocal leukoencephalopathy in AIDS: are there any MR findings useful to patient management and predictive of patient survival? AIDS Clinical Trials Group, 243 Team.艾滋病相关的进行性多灶性白质脑病:是否存在对患者管理有用且能预测患者生存的磁共振成像表现?艾滋病临床试验组,243团队
AJNR Am J Neuroradiol. 1999 Nov-Dec;20(10):1896-906.
10
Progressive diffuse leukoencephalopathy in patients with acquired immune deficiency syndrome (AIDS).获得性免疫缺陷综合征(艾滋病)患者的进行性弥漫性白质脑病。
Acta Neuropathol. 1985;68(4):333-9. doi: 10.1007/BF00690837.