Dougherty J M, McCulley J P
Br J Ophthalmol. 1984 Aug;68(8):524-8. doi: 10.1136/bjo.68.8.524.
One hundred and fifteen patients with chronic blepharitis were compared with 47 normal controls. Six clinically distinct groups of blepharitis were observed: staphylococcal; seborrhoeic, alone, with associated staphylococcal superinfection, meibomian seborrhoea, or secondary inflammation of the meibomian glands; and meibomian keratoconjunctivitis (MKC). Staphylococcus aureus was isolated in appreciable frequency from the staphylococcal and the mixed staphylococcal/seborrhoeic groups in contrast to the normal and non-staphylococcal groups. Coagulase-negative Staphylococcus spp., Propionibacterium acnes, and cornyneform bacteria were the most commonly isolated bacteria from the lid for all groups. Cultures of material expressed from the meibomian glands yielded similar organisms but in reduced frequency. Testing of antibiotic susceptibility revealed Staph aureus to be usually sensitive to most commonly used ophthalmic antimicrobials except sulphonamides.
115例慢性睑缘炎患者与47名正常对照者进行了比较。观察到6种临床上不同的睑缘炎类型：葡萄球菌性；脂溢性，单独存在、伴有相关葡萄球菌重叠感染、睑板腺脂溢、或睑板腺继发性炎症；以及睑板腺角膜结膜炎（MKC）。与正常组和非葡萄球菌组相比，金黄色葡萄球菌在葡萄球菌性和葡萄球菌/脂溢性混合组中的分离频率较高。凝固酶阴性葡萄球菌属、痤疮丙酸杆菌和棒状杆菌是所有组中从眼睑分离出的最常见细菌。从睑板腺挤出物的培养物中也分离出类似的微生物，但频率较低。抗生素敏感性测试显示，除磺胺类药物外，金黄色葡萄球菌通常对大多数常用眼科抗菌药物敏感。
