Matsuda S
Biol Res Pregnancy Perinatol. 1984;5(2):57-60.
Thirty antibiotics, including penicillins, cephems, chloramphenicol, tetracyclines, macrolides, and aminoglycosides, were given p.o., i.m. or i.v. once to 70 puerperal women to compare milk drug levels with serum levels over a 6-h period. Antibiotic transfer into the milk was small. No drugs except for a few (chloramphenicol, tetracyclines, macrolides) reached the level of 1 mcg/ml or greater. Penicillins and cephams detected in trace amounts in the milk are likely to have little effect on infants.
给70名产妇口服、肌肉注射或静脉注射30种抗生素，包括青霉素类、头孢菌素类、氯霉素、四环素类、大环内酯类和氨基糖苷类，以比较6小时内乳汁中的药物水平与血清水平。抗生素向乳汁中的转移量很小。除少数几种（氯霉素、四环素类、大环内酯类）外，没有药物达到1微克/毫升或更高的水平。乳汁中检测到的微量青霉素类和头孢菌素类药物可能对婴儿影响很小。
