在淋病治疗中，在单剂量氨苄西林和丙磺舒基础上加用一个疗程四环素的优势。
Advantages of adding a course of tetracycline to single dose ampicillin and probenecid in the treatment of gonorrhoea.
作者信息
Ridgway G L, Oriel J D
出版信息
Br J Vener Dis. 1984 Aug;60(4):235-7. doi: 10.1136/sti.60.4.235.
Chlamydia trachomatis was reisolated from 11 of 12 men with gonorrhoea who had initially yielded chlamydiae and who had been treated with ampicillin and probenecid (AMP) only, but from none of five such men treated with ampicillin and probenecid followed by tetracycline (AMPT). These results correlated with the absence of postgonococcal urethritis (PGU) in the group treated with AMPT. C trachomatis was isolated or reisolated from 20 of 25 women after treatment with AMP, compared with none of 14 women treated with AMPT. We recommend the addition of a course of tetracycline to the routine single dose treatment for gonorrhoea in men and women.
从12名患有淋病且最初检出衣原体、仅接受过氨苄青霉素和丙磺舒（AMP）治疗的男性中，有11人再次分离出沙眼衣原体，但在5名接受氨苄青霉素和丙磺舒治疗后又接受四环素治疗（AMPT）的此类男性中，无人再次分离出沙眼衣原体。这些结果与接受AMPT治疗组中无淋菌性尿道炎（PGU）相符。接受AMP治疗的25名女性中有20人分离出或再次分离出沙眼衣原体，而接受AMPT治疗的14名女性中无人分离出。我们建议在男女淋病常规单剂量治疗中加用一个疗程的四环素。
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