Nalwa V, Rao P S
Clin Exp Pharmacol Physiol. 1984 May-Jun;11(3):261-7. doi: 10.1111/j.1440-1681.1984.tb00263.x.
Six rats bar-pressed for intracranial self-stimulation in a Skinner box on fixed interval and differential reinforcement of low rate schedules with an interval parameter of 1.3 s. After amphetamine timing efficiency was reduced immediately on both the schedules; it recovered after 60 min on the DRL schedule but not within 120 min on the FI schedule. Response rates increased on both the schedules. The increased response rates correlated with the low efficiency on the DRL but not on the FI schedule. The selective sparing of DRL performance is in line with the similarity between the effects of amphetamine and frontal cortical lesions.
六只大鼠在斯金纳箱中，按照固定间隔和低比率强化程序进行操作，间隔参数为1.3秒，通过按压杠杆进行颅内自我刺激。给予苯丙胺后，两种程序下的定时效率立即降低；在DRL程序中，60分钟后恢复，但在FI程序中120分钟内未恢复。两种程序下的反应率均增加。DRL程序中增加的反应率与效率低下相关，而FI程序中则不然。DRL表现的选择性保留与苯丙胺和额叶皮质损伤的效应相似性一致。
