Rosin M A, Braun M
Cutis. 1984 Jun;33(6):572-4.
A patient with Parkinson's disease developed a malignant melanoma within a congenital nevus after starting levodopa therapy. Levodopa has a central role in the metabolism of the melanocyte but data do not permit the conclusion that it promotes the development of malignant melanoma. However, patients receiving levodopa should be monitored for skin changes suggestive of melanoma.
一名帕金森病患者在开始左旋多巴治疗后，其先天性痣内出现了恶性黑色素瘤。左旋多巴在黑素细胞代谢中起核心作用，但现有数据尚不能得出其会促进恶性黑色素瘤发生的结论。然而，接受左旋多巴治疗的患者应接受监测，观察是否有提示黑色素瘤的皮肤变化。
