Holdstock G, DuBoulay C E, Smith C L
Dig Dis Sci. 1984 Aug;29(8):731-4. doi: 10.1007/BF01312946.
In a survey of patients with inflammatory bowel disease (IBD), colonoscopy with multiple biopsies has been shown to be superior to either colonoscopy alone or barium studies in assessing disease extent. Thus, of a total of 149 patients, 23 (15%) were considered to have total colitis on barium enema, 51 (34%) on macroscopic colonoscopy appearance compared to 92 (62%) on biopsy. Furthermore, radiological assessment of "skip lesions" was shown to be unreliable. Although it remains to be seen whether the more accurate delineation of disease extent achieved by endoscopy is advantageous in terms of clinical management, it may have implications for our understanding of the disease.
在一项针对炎症性肠病（IBD）患者的调查中，已表明进行多次活检的结肠镜检查在评估疾病范围方面优于单纯的结肠镜检查或钡剂造影检查。因此，在总共149例患者中，钡剂灌肠显示23例（15%）患有全结肠炎，宏观结肠镜检查显示51例（34%）患有全结肠炎，而活检显示92例（62%）患有全结肠炎。此外，“跳跃性病变”的放射学评估被证明是不可靠的。虽然内镜检查对疾病范围的更准确界定在临床管理方面是否有利还有待观察，但这可能会影响我们对该疾病的理解。
