Seidel C L, Allen J C, Mukhopadhyay A
Experientia. 1984 Jul 15;40(7):691-2. doi: 10.1007/BF01949725.
The purpose of these experiments was to compare the contractile response to ACh of stomach fundal strips from hypertensive (SHR) and normotensive (WKY) rats during the development of hypertension. The results indicate that the reactivity to ACh is the same in fundal strips from young SHR and WKY rats; however, with maturation strips from WKY rats undergo a reduction in responsiveness which does not occur in the SHR. Therefore, strips from older SHR rats are more reactive to ACh than are those from age matched WKY rats.
这些实验的目的是比较高血压大鼠（SHR）和正常血压大鼠（WKY）胃底条在高血压发展过程中对乙酰胆碱（ACh）的收缩反应。结果表明，年轻的SHR大鼠和WKY大鼠胃底条对ACh的反应性相同；然而，随着成熟，WKY大鼠的胃底条反应性降低，而SHR大鼠则不会。因此，老年SHR大鼠的胃底条对ACh的反应性比年龄匹配的WKY大鼠的胃底条更高。
