Dobrev R P, Vladimirov B J
Int Orthop. 1984;7(4):243-50. doi: 10.1007/BF00266835.
Investigation in the field of electrophysiology shows that bioelectric phenomena of different origin are present in bone, the most important being the bioelectric potential connected with bone viability and metabolism. The negative biopotential is high at the fracture site where metabolism is also increased. During healing the negative values decrease and when it is complete the configuration of biopotentials along the length of the bone regains the pattern characteristic of intact bone. Negative biopotentials are needed to achieve callus formation and they disappear when healing has occurred. A metal device is used for osteosynthesis to obtain stable fixation of the fragments, but the electroconductive metal produces a 'short-circuit' of biopotentials along its length, so depriving the bone of necessary negative biopotential. Consequently the intensity of the metabolic processes is also reduced, leading to a relative delay in callus formation. Although a plaster cast may fail to provide adequate stability the natural electrophysiological conditions are preserved, and the period of callus formation is shortened. The negative biopotentials required for fracture union may be preserved by using non-conductive (dielectric) implants to achieve stable osteosynthesis.
电生理学领域的研究表明,骨骼中存在不同来源的生物电现象,其中最重要的是与骨骼活力和代谢相关的生物电位。骨折部位的负生物电位较高,此处的代谢也会增强。在愈合过程中,负值会降低,当愈合完成时,沿骨骼长度方向的生物电位配置会恢复到完整骨骼的特征模式。实现骨痂形成需要负生物电位,而愈合发生时它们会消失。金属装置用于骨固定以获得骨折碎片的稳定固定,但导电金属会沿其长度产生生物电位的“短路”,从而使骨骼失去必要的负生物电位。因此,代谢过程的强度也会降低,导致骨痂形成相对延迟。虽然石膏固定可能无法提供足够的稳定性,但自然电生理条件得以保留,骨痂形成期会缩短。通过使用非导电(介电)植入物实现稳定的骨固定,可以保留骨折愈合所需的负生物电位。