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[脉络膜恶性黑色素瘤结构的超声研究]

[Echographic study of the structure of a malignant melanoma of the choroid].

作者信息

Marchini G, Beltramello A, Doglioni C

出版信息

J Fr Ophtalmol. 1984;7(3):227-31.

PMID:6747215
Abstract

The case of a 74 yr. old male affected by a mixed cell choroidal melanoma is reported. Ophthalmoscopic examination suggested a choroidal melanoma; this diagnosis was confirmed by fluorescein angiography, ultrasonography and CT-scan. In particular, contact ultrasonography (A-mode and B-mode), following topographic, kinetic and quantitative diagnostic criteria, revealed a solid lesion with the typical features of a choroidal melanoma. Ultrasonography by differential selective echographic technique revealed that the lesion consisted of two components with different acoustic features : the first characterized by a 41 dB reflectivity (peripheral and superior portions), the second by a 23 dB reflectivity (central and inferior portions). Attenuation values were 1.2 dB/mm and 0.7 dB/mm, respectively. CT-scan did not show any significant change in density within the mass. Histopathologic evaluation confirmed a clear-cut edge between the epitheloid and the spindle-cell components. The more reflecting lesion (23 dB), located in the central-inferior portion of the lesion, was histologically less dense and was due to the epitheloid component. The superiorally located more attenuating lesion (1.2 dB/mm) was histologically more dense and due to the spindle-cell component.

摘要

报告了一例74岁男性患有混合细胞脉络膜黑色素瘤的病例。眼底镜检查提示脉络膜黑色素瘤;荧光素血管造影、超声检查和CT扫描证实了这一诊断。特别是,接触式超声检查(A模式和B模式)按照地形、动力学和定量诊断标准,显示出一个具有脉络膜黑色素瘤典型特征的实性病变。采用差选超声造影技术的超声检查显示,该病变由两个具有不同声学特征的成分组成:第一个成分的特征是反射率为41dB(周边和上部),第二个成分的特征是反射率为23dB(中央和下部)。衰减值分别为1.2dB/mm和0.7dB/mm。CT扫描未显示肿块内密度有任何显著变化。组织病理学评估证实上皮样细胞成分和梭形细胞成分之间有清晰的边界。位于病变中央下部的反射性更强的病变(23dB),组织学上密度较低,由上皮样细胞成分构成。位于上部的衰减性更强的病变(1.2dB/mm),组织学上密度更高,由梭形细胞成分构成。

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