Sallet G, Serop S, Verbraeken H, Hanssens M
Dept. of Ophthalmology, University hospital Ghent, Belgium.
Bull Soc Belge Ophtalmol. 1993;248:53-8.
The major goal in the evaluation of posterior uveal tumours is to determine whether an intra-ocular malignancy is present and whether intervention is necessary. Small uveal pigmented tumours can safely be managed by observation until growth is documented. However, extensive evaluation for each suspicious lesion is necessary in order not to miss any signs of malignancy. A case is presented of a 41 year old male patient with orbital pain as initial symptom of a choroidal melanoma. Fluorescein-angiography revealed signs of double circulation. Abnormal choroidal vessels inside the tumour showed up clearly on indocyanine-green angiography. By ultrasonography we were able to detect scleral perforation and extra-scleral extension. Computed tomography confirmed the extra-scleral extension. As there were no signs of metastasis, an orbital exenteration with sparing of the eyelids was performed. Histopathology is compared with the results of clinical investigation.
评估后葡萄膜肿瘤的主要目标是确定眼内是否存在恶性肿瘤以及是否需要进行干预。小的葡萄膜色素性肿瘤在记录到生长之前可通过观察安全处理。然而,对每个可疑病变进行广泛评估是必要的,以免遗漏任何恶性迹象。本文介绍了一例41岁男性患者,以眼眶疼痛为脉络膜黑色素瘤的初始症状。荧光素血管造影显示双循环迹象。肿瘤内异常的脉络膜血管在吲哚菁绿血管造影中清晰可见。通过超声检查,我们能够检测到巩膜穿孔和巩膜外扩展。计算机断层扫描证实了巩膜外扩展。由于没有转移迹象,进行了保留眼睑的眼眶内容物剜除术。将组织病理学结果与临床研究结果进行了比较。