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岛根县过去10年(1972 - 1981年)子宫癌大规模筛查的进展——细胞采样方法及中央细胞学诊断系统

[Developments in mass screening for uterine cancer in the past 10 years (1972-1981) in Shimane Prefecture--cell sampling method and the central cytological diagnostic system].

作者信息

Iwanari O, Matsunaga I, Moriyama M, Takahashi K, Kitao M

出版信息

Nihon Sanka Fujinka Gakkai Zasshi. 1984 Jul;36(7):1008-16.

PMID:6747385
Abstract

Mass screenings for uterine cancer have been done on 200,000 women in Shimane Prefecture, Japan, from 1972-1981. Up to 1978, a cotton-tipped applicator was used for sample procurement and since that time a wooden spatula type instrument has been used. A central, cytological diagnostic system has been used since 1979. The cytology activity index (CAI) was about 90 each year. The rate of second examination performed is about 60% for women requiring an accurate examination. Cancer detection rates increased from 0.05% to 0.12%, the false negative rate decreased, cytological and histological findings were in close parallel and the mortality rates have decreased. These positive results are attributed to the use of the wooden spatula and central diagnostic systems. By the mass screening for uterine cancer during these 10 years, 81 women were detected as having carcinoma in situ and 107 women as having invasive carcinoma in the histological findings. The number of first screenings has decreased gradually, but the number examined 6 times or more has increased. These results include that same women have tended to undergo the mass screening examination. In women over 50 y.o., particularly those 60 or over, the number screened was low, yet the incidence of invasive cancer exceeded that in other groups.

摘要

1972年至1981年期间,日本岛根县对20万名女性进行了子宫癌大规模筛查。截至1978年,使用棉拭子采集样本,自那时起开始使用木质刮板型器械。自1979年起采用中央细胞学诊断系统。每年的细胞学活动指数(CAI)约为90。对于需要精确检查的女性,二次检查率约为60%。癌症检出率从0.05%上升至0.12%,假阴性率下降,细胞学和组织学检查结果高度一致,死亡率也有所下降。这些积极成果归功于木质刮板和中央诊断系统的使用。在这10年的子宫癌大规模筛查中,组织学检查发现81名女性患有原位癌,107名女性患有浸润癌。首次筛查的人数逐渐减少,但接受6次及以上检查的人数有所增加。这些结果表明,同一批女性倾向于接受大规模筛查检查。在50岁以上的女性中,尤其是60岁及以上的女性,筛查人数较少,但浸润癌的发病率超过了其他群体。

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