Crouse S F, Hooper P L, Atterbom H A, Papenfuss R L
JAMA. 1984 Aug 10;252(6):785-7.
The finding that high doses (160 mg) of zinc lowered high-density lipoprotein-cholesterol prompted us to study the effect of low-dose zinc supplementation on lipoprotein values in sedentary and endurance-trained men. Twenty-one endurance-trained and 23 sedentary men received either placebo or 50 mg of zinc sulfate daily for eight weeks. Despite the fact that plasma zinc increased 15%, fasting plasma high-density-lipoprotein cholesterol, total cholesterol, low-density-lipoprotein cholesterol, and triglyceride levels did not change in response to zinc ingestion. We conclude that low-dose zinc supplementation does not affect lipid or lipoprotein values in either endurance-trained or sedentary men.
高剂量（160毫克）锌会降低高密度脂蛋白胆固醇这一发现促使我们研究低剂量补锌对久坐不动的男性和耐力训练男性脂蛋白值的影响。21名耐力训练男性和23名久坐不动的男性每天接受安慰剂或50毫克硫酸锌，持续八周。尽管血浆锌增加了15%，但空腹血浆高密度脂蛋白胆固醇、总胆固醇、低密度脂蛋白胆固醇和甘油三酯水平并未因摄入锌而发生变化。我们得出结论，低剂量补锌对耐力训练男性或久坐不动的男性的血脂或脂蛋白值没有影响。
