Miura T, Tsuchihashi K, Yoshida E, Kobayashi K, Shimamoto K, Iimura O
Jpn J Med. 1984 Feb;23(1):22-6. doi: 10.2169/internalmedicine1962.23.22.
In order to assess the relationship of electrocardiographic (ECG) changes in acute cerebrovascular accidents (CVA) to the locations of the cerebral lesions, ECG records and brain computerized tomographic (CT) scans which were taken within 48 hours of CVA onset were examined in 39 patients without heart disease and/or treatment with cardiovascular drugs. The ECG was normal in 25% (3/12) of basal ganglial CVA, 22% (2/9) of frontal CVA and 36% (4/11) of temporo-parietal CVA. Nonspecific ST-T changes occurred in basal ganglial CVA (25%), frontal CVA (22%), temporo-parietal CVA (18%) and in the other categories of CVA locations. Corrected QT interval (QTc) elongation was observed not only in frontal (22%), but also in basal ganglial CVA (25%), temporo-parietal CVA (36%) and cerebellar CVA (50%). There were no ECG changes specific to a particular CVA location. These findings suggest that widely distributed neurons and pathways within the central nervous system may influence ECG.
为了评估急性脑血管意外（CVA）时心电图（ECG）变化与脑病变部位的关系，我们对39例无心脏病和/或未接受心血管药物治疗的患者进行了研究，这些患者在CVA发病后48小时内进行了ECG记录和脑部计算机断层扫描（CT）。基底节区CVA患者中25%（3/12）的ECG正常，额叶CVA患者中22%（2/9）的ECG正常，颞顶叶CVA患者中36%（4/11）的ECG正常。非特异性ST-T改变出现在基底节区CVA（25%）、额叶CVA（22%）、颞顶叶CVA（18%）以及其他CVA部位类别中。不仅在额叶CVA（22%）中观察到校正QT间期（QTc）延长，在基底节区CVA（25%）、颞顶叶CVA（36%）和小脑CVA（50%）中也观察到QTc延长。没有特定于某个CVA部位的ECG变化。这些发现表明，中枢神经系统内广泛分布的神经元和通路可能影响ECG。
