Ducos J, Garretta M, Marty Y
Rev Fr Transfus Immunohematol. 1978 Mar;21(2):423-30. doi: 10.1016/s0338-4535(78)80080-4.
We report here the experience of 3 years of irregular antibody automated screening with Groupamatic, that is to say of 661,511 samples tested in Paris and 269, 162 samples tested in Toulouse. The positive reactions in Paris were 16,296 (2.46%) out of which 2,021 irregular antibodies were identified (0.30%). The positive reactions in Toulouse were 8,266 (3.07%) out of which 2,138 irregular antibodies were identified (0,79%). The difference between the number of screened positive reactions and the identified one is due to false positive reactions (half of the cases) and to autoantibodies whose number is roughly the same than the number of identified alloantibodies. During the years 1970, 1971 and 1972, the irregular antibodies were systematically screened in Toulouse on all blood donors with a manual technique on opaline plate using enzyme treated red cell tests (papain). 7,147 positive reactions were detected, out of 240,080 tests (2.98%). 1,954 (0,81%) were alloantibodies and 1,529 (0.64%) autoantibodies; 3.455 were false positive reactions and 209 were non identified antibodies. These figures are superimposed with those obtained with Groupamatic during the following years, thus pointing out the interest of this equipment.
我们在此报告使用Groupamatic进行3年不规则抗体自动筛查的经验，即在巴黎检测了661,511份样本，在图卢兹检测了269,162份样本。巴黎的阳性反应有16,296例（2.46%），其中鉴定出2,021例不规则抗体（0.30%）。图卢兹的阳性反应有8,266例（3.07%），其中鉴定出2,138例不规则抗体（0.79%）。筛查出的阳性反应数量与鉴定出的阳性反应数量之间的差异是由于假阳性反应（半数情况）以及自身抗体，自身抗体的数量与鉴定出的同种抗体数量大致相同。在1970年、1971年和1972年期间，图卢兹对所有献血者使用酶处理红细胞试验（木瓜蛋白酶）在乳白平板上采用手工技术系统筛查不规则抗体。在240,080次检测中检测到7,147例阳性反应（2.98%）。1,954例（0.81%）为同种抗体，1,529例（0.64%）为自身抗体；3,455例为假阳性反应，209例为未鉴定抗体。这些数字与随后几年使用Groupamatic获得的数字相符，从而表明了该设备的价值。
