• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The mitochondrial glycine cleavage system. Unique features of the glycine decarboxylation.

作者信息

Kikuchi G, Hiraga K

出版信息

Mol Cell Biochem. 1982 Jun 25;45(3):137-49. doi: 10.1007/BF00230082.

DOI:10.1007/BF00230082
PMID:6750353
Abstract
摘要

相似文献

1
The mitochondrial glycine cleavage system. Unique features of the glycine decarboxylation.线粒体甘氨酸裂解系统。甘氨酸脱羧作用的独特特征。
Mol Cell Biochem. 1982 Jun 25;45(3):137-49. doi: 10.1007/BF00230082.
2
Resolution and characterization of the glycine-cleavage reaction in pea leaf mitochondria. Properties of the forward reaction catalysed by glycine decarboxylase and serine hydroxymethyltransferase.豌豆叶片线粒体中甘氨酸裂解反应的解析与表征。甘氨酸脱羧酶和丝氨酸羟甲基转移酶催化的正向反应特性。
Biochem J. 1988 Oct 1;255(1):169-78. doi: 10.1042/bj2550169.
3
The mitochondrial glycine cleavage system. Functional association of glycine decarboxylase and aminomethyl carrier protein.线粒体甘氨酸裂解系统。甘氨酸脱羧酶与氨甲基载体蛋白的功能关联。
J Biol Chem. 1980 Dec 25;255(24):11671-6.
4
The mitochondrial glycine cleavage system. Purification and properties of glycine decarboxylase from chicken liver mitochondria.线粒体甘氨酸裂解系统。鸡肝线粒体中甘氨酸脱羧酶的纯化及性质
J Biol Chem. 1980 Dec 25;255(24):11664-70.
5
Inhibition of glycine oxidation by pyruvate, alpha-ketoglutarate, and branched-chain alpha-keto acids in rat liver mitochondria: presence of interaction between the glycine cleavage system and alpha-keto acid dehydrogenase complexes.丙酮酸、α-酮戊二酸和支链α-酮酸对大鼠肝线粒体甘氨酸氧化的抑制作用：甘氨酸裂解系统与α-酮酸脱氢酶复合物之间存在相互作用。
Arch Biochem Biophys. 1986 Sep;249(2):263-72. doi: 10.1016/0003-9861(86)90002-0.
6
The glycine decarboxylase system: a fascinating complex.甘氨酸脱羧酶系统：一个迷人的复合体。
Trends Plant Sci. 2001 Apr;6(4):167-76. doi: 10.1016/s1360-1385(01)01892-1.
7
Regulation of hepatic glycine catabolism by glucagon.胰高血糖素对肝脏甘氨酸分解代谢的调节。
J Biol Chem. 1989 Feb 25;264(6):3347-51.
8
Role of the glycine-cleavage system in glycine and serine metabolism in various organs.甘氨酸裂解系统在各器官甘氨酸和丝氨酸代谢中的作用。
Biochem Soc Trans. 1980 Oct;8(5):504-6. doi: 10.1042/bst0080504.
9
Purification and properties of glycine decarboxylase, a component of the glycine cleavage system, from rat liver mitochondria and immunochemical comparison of this enzyme from various sources.大鼠肝线粒体中甘氨酸裂解系统的组成成分甘氨酸脱羧酶的纯化及性质，以及不同来源该酶的免疫化学比较
J Biochem. 1980 Oct;88(4):1193-9. doi: 10.1093/oxfordjournals.jbchem.a133074.
10
Mechanism of the glycine cleavage reaction: retention of C-2 hydrogens of glycine on the intermediate attached to H-protein and evidence for the inability of serine hydroxymethyltransferase to catalyze the glycine decarboxylation.甘氨酸裂解反应的机制：甘氨酸C-2位氢原子在与H蛋白相连的中间体上的保留以及丝氨酸羟甲基转移酶无法催化甘氨酸脱羧反应的证据。
Arch Biochem Biophys. 1986 Nov 15;251(1):121-7. doi: 10.1016/0003-9861(86)90058-5.

引用本文的文献

1
Role of ammonia-lyases in the synthesis of the dithiomethylamine ligand during [FeFe]-hydrogenase maturation.氨裂解酶在 [FeFe]-氢化酶成熟过程中合成二硫甲基胺配体中的作用。
J Biol Chem. 2024 Oct;300(10):107760. doi: 10.1016/j.jbc.2024.107760. Epub 2024 Sep 10.
2
A new mechanism for cannabidiol in regulating the one-carbon cycle and methionine levels in Dictyostelium and in mammalian epilepsy models.大麻二酚在调节盘基网柄菌及哺乳动物癫痫模型中的一碳循环和蛋氨酸水平方面的新机制。
Br J Pharmacol. 2020 Feb;177(4):912-928. doi: 10.1111/bph.14892. Epub 2020 Jan 3.
3
Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants.

本文引用的文献

1
Metabolism of glycine by avian liver.禽类肝脏对甘氨酸的代谢
J Biol Chem. 1962 Jan;237:99-103.
2
SERINE TRANSHYDROXYMETHYLASE. PROPERTIES OF THE ENZYME-SUBSTRATE COMPLEXES OF D-ALANINE AND GLYCINE.
J Biol Chem. 1964 Nov;239:3801-7.
3
STUDIES ON WHEAT PLANTS USING CARBON-14 COMPOUNDS. XXI. THE METABOLISM OF GLYCINE-2-C14.使用碳 - 14化合物对小麦植株的研究。第二十一部分。甘氨酸 - 2 - C14的代谢
Can J Biochem. 1964 Sep;42:1293-9. doi: 10.1139/o64-138.
通过对致病酶变体的结构分析揭示人类二氢硫辛酰胺脱氢酶缺乏症的潜在分子改变。
Hum Mol Genet. 2019 Oct 15;28(20):3339-3354. doi: 10.1093/hmg/ddz177.
4
Administration of 5-methoxyindole-2-carboxylic acid that potentially targets mitochondrial dihydrolipoamide dehydrogenase confers cerebral preconditioning against ischemic stroke injury.5-甲氧基色胺-2-羧酸给药，可能靶向线粒体二氢硫辛酰胺脱氢酶，赋予脑预处理对缺血性中风损伤的保护作用。
Free Radic Biol Med. 2017 Dec;113:244-254. doi: 10.1016/j.freeradbiomed.2017.10.008. Epub 2017 Oct 7.
5
Alternative Oxidase Transcription Factors AOD2 and AOD5 of Control the Expression of Genes Involved in Energy Production and Metabolism.交替氧化酶转录因子AOD2和AOD5调控参与能量产生和代谢的基因表达。
G3 (Bethesda). 2017 Feb 9;7(2):449-466. doi: 10.1534/g3.116.035402.
6
Mitochondrial Dihydrolipoamide Dehydrogenase is Upregulated in Response to Intermittent Hypoxic Preconditioning.线粒体二氢硫辛酰胺脱氢酶在间歇性低氧预处理反应中上调。
Int J Med Sci. 2015 May 23;12(5):432-40. doi: 10.7150/ijms.11402. eCollection 2015.
7
Metabolic heterogeneity of follicular amino acids in polycystic ovary syndrome is affected by obesity and related to pregnancy outcome.多囊卵巢综合征中卵泡氨基酸的代谢异质性受肥胖影响且与妊娠结局相关。
BMC Pregnancy Childbirth. 2014 Jan 10;14:11. doi: 10.1186/1471-2393-14-11.
8
Structure of the homodimeric glycine decarboxylase P-protein from Synechocystis sp. PCC 6803 suggests a mechanism for redox regulation.来自集胞藻 PCC 6803 的同二聚体甘氨酸脱羧酶 P 蛋白的结构提示了一种氧化还原调控的机制。
J Biol Chem. 2013 Dec 6;288(49):35333-45. doi: 10.1074/jbc.M113.509976. Epub 2013 Oct 11.
9
Glycine cleavage system: reaction mechanism, physiological significance, and hyperglycinemia.甘氨酸裂解系统：反应机制、生理意义及高甘氨酸血症
Proc Jpn Acad Ser B Phys Biol Sci. 2008;84(7):246-63. doi: 10.2183/pjab.84.246.
10
Effect of High Physiological Temperatures on NAD+ Content of Green Leaf Mitochondria (Apparent Inhibition of Glycine Oxidation).高生理温度对绿叶线粒体NAD⁺含量的影响（对甘氨酸氧化的明显抑制）。
Plant Physiol. 1993 Aug;102(4):1157-1162. doi: 10.1104/pp.102.4.1157.
4
alpha-Keto acid dehydrogenation complexes. IV. Resolution and reconstitution of the Escherichia coli pyruvate dehydrogenation complex.α-酮酸脱氢酶复合体。IV. 大肠杆菌丙酮酸脱氢酶复合体的拆分与重组。
J Biol Chem. 1963 Jan;238:30-9.
5
Intermediatry metabolism of Diplococcus glycinophilus. I. Glycine cleavage and one-carbon interconversions.甘氨酸嗜双球菌的中间代谢。I. 甘氨酸裂解和一碳相互转化。
J Bacteriol. 1961 Apr;81(4):541-9. doi: 10.1128/jb.81.4.541-549.1961.
6
Deuterium studies on the mechanism of enzymatic amino acid decarboxylation.氘对酶促氨基酸脱羧作用机制的研究。
J Biol Chem. 1954 Jul;209(1):327-36.
7
The mitochondrial glycine cleavage system. Functional association of glycine decarboxylase and aminomethyl carrier protein.线粒体甘氨酸裂解系统。甘氨酸脱羧酶与氨甲基载体蛋白的功能关联。
J Biol Chem. 1980 Dec 25;255(24):11671-6.
8
The mitochondrial glycine cleavage system. Purification and properties of glycine decarboxylase from chicken liver mitochondria.线粒体甘氨酸裂解系统。鸡肝线粒体中甘氨酸脱羧酶的纯化及性质
J Biol Chem. 1980 Dec 25;255(24):11664-70.
9
Defective glycine cleavage system in nonketotic hyperglycinemia. Occurrence of a less active glycine decarboxylase and an abnormal aminomethyl carrier protein.非酮症高甘氨酸血症中甘氨酸裂解系统缺陷。存在活性较低的甘氨酸脱羧酶和异常的氨基甲基载体蛋白。
J Clin Invest. 1981 Aug;68(2):525-34. doi: 10.1172/jci110284.
10
Purification and properties of glycine decarboxylase, a component of the glycine cleavage system, from rat liver mitochondria and immunochemical comparison of this enzyme from various sources.大鼠肝线粒体中甘氨酸裂解系统的组成成分甘氨酸脱羧酶的纯化及性质，以及不同来源该酶的免疫化学比较
J Biochem. 1980 Oct;88(4):1193-9. doi: 10.1093/oxfordjournals.jbchem.a133074.