Handlers J P, Melrose R J, Abrams A M, Taylor C R
Oral Surg Oral Med Oral Pathol. 1982 Aug;54(2):207-12. doi: 10.1016/0030-4220(82)90218-3.
Five cases of oral pemphigus vulgaris, diagnosed on the basis of clinical, histopathologic, and immunopathologic criteria, were selected. Sections were stained with the peroxidase antiperoxidase (PAP) technique of immunocytochemical staining. The findings correlated well with those reported by direct immunofluorescence demonstrating the same intercellular substance (ICS) pattern of staining. Because this staining technique is applied to routinely processed and paraffinized tissue, it may be of particular value to the oral pathologist who often receives formalin-fixed material before the need for immunopathologic studies is recognized. In addition, interpretation does not require specialized microscopy and tissue sections can be stored and retrieved for retrospective study.
选取了5例根据临床、组织病理学和免疫病理学标准诊断的寻常型口腔天疱疮病例。切片采用免疫细胞化学染色的过氧化物酶抗过氧化物酶（PAP）技术进行染色。这些结果与直接免疫荧光报告的结果密切相关，显示出相同的细胞间物质（ICS）染色模式。由于这种染色技术适用于常规处理和石蜡包埋的组织，对于经常在认识到需要进行免疫病理学研究之前收到福尔马林固定材料的口腔病理学家来说，它可能具有特殊价值。此外，解读不需要专门的显微镜检查，组织切片可以储存和检索用于回顾性研究。
