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癌症患者血清中的福斯曼抗体水平。

Forssman antibody levels in sera of cancer patients.

作者信息

Mori T, Fujii G, Kawamura A, Yasuda T, Naito Y, Tsumita T

出版信息

Immunol Commun. 1982;11(3):217-25. doi: 10.3109/08820138209094132.

DOI:10.3109/08820138209094132
PMID:6754580
Abstract

By means of SRBC lysis in agarose gel and Forssman (F) liposome lysis assay, serum levels of F antibodies were determined in various cancer patients. F antibody titers of the patient's sera were shown to be lower than that of normal controls. Following radical surgery, F antibody titers were elevated significantly in most of the patients with advanced gastric, colorectal and lung cancer. Similar tends of anti-A antibody titers were observed in group O and B patients with advanced cancer.

摘要

通过琼脂糖凝胶中的SRBC裂解和福斯曼（F）脂质体裂解试验，测定了各类癌症患者血清中F抗体的水平。结果显示，患者血清的F抗体滴度低于正常对照组。在接受根治性手术后，大多数晚期胃癌、结直肠癌和肺癌患者的F抗体滴度显著升高。在O型和B型晚期癌症患者中也观察到了类似的抗A抗体滴度变化趋势。

相似文献

1
Forssman antibody levels in sera of cancer patients.癌症患者血清中的福斯曼抗体水平。
Immunol Commun. 1982;11(3):217-25. doi: 10.3109/08820138209094132.
2
[Antibodies to Forssman antigen in patients with cancer of the gastrointestinal tract and breast].[胃肠道和乳腺癌患者中福斯曼抗原抗体]
Ter Arkh. 1986;58(9):99-102.
3
Forssman-like antibody levels in sera of patients with lung cancer.
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4
Immunochemical determination of Forssman and blood group A-active glycolipids in human gastric mucosa by inhibition assay of liposome lysis.
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Cardiotoxicity of Forssman antibodies in in vitro perfusion experiments.福斯曼抗体在体外灌注实验中的心脏毒性
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The relation of serum anti-(GalNAc beta) and -para-Forssman disaccharide IgG levels to the progression and histological grading of gastrointestinal cancer.血清抗（β-N-乙酰半乳糖胺）和抗对福斯曼二糖IgG水平与胃肠道癌进展及组织学分级的关系
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7
Characterization of anti-Forssman (anti-Fs) antibodies in human sera: their specificity and possible changes in patients with cancer.人血清中抗福斯曼（anti-Fs）抗体的特性：其特异性及癌症患者体内可能的变化。
J Immunol. 1979 Jul;123(1):92-6.
8
[Forssman antigen in cancerous and normal human tissues].[人癌组织和正常组织中的福斯曼抗原]
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A human B-cell line (BES-1) forming rosettes with sheep erythrocytes, producing Forssman antibody, and phagocytizing sheep erythrocytes.一种人B细胞系（BES-1），它能与绵羊红细胞形成玫瑰花结，产生福斯曼抗体，并吞噬绵羊红细胞。
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引用本文的文献

1
ABO blood group A transferase and its codon 69 substitution enzymes synthesize FORS1 antigen of FORS blood group system.ABO 血型 A 转移酶及其 69 号密码子取代酶合成 FORS 血型系统的 FORS1 抗原。
Sci Rep. 2019 Jul 4;9(1):9717. doi: 10.1038/s41598-019-46029-7.
2
Blood group gene-encoded A transferase catalyzes the biosynthesis of FORS1 antigen of FORS system upon Met69Thr/Ser substitution.血型基因编码 A 转移酶在 Met69Thr/Ser 取代时催化 FORS 系统 FORS1 抗原的生物合成。
Blood Adv. 2018 Jun 26;2(12):1371-1381. doi: 10.1182/bloodadvances.2018017293.
3
ABO blood group A transferases catalyze the biosynthesis of FORS blood group FORS1 antigen upon deletion of exon 3 or 4.
ABO血型A转移酶在第3或4外显子缺失时催化FORS血型FORS1抗原的生物合成。
Blood Adv. 2017 Dec 20;1(27):2756-2766. doi: 10.1182/bloodadvances.2017009795. eCollection 2017 Dec 26.
4
Crosstalk between ABO and Forssman (FORS) blood group systems: FORS1 antigen synthesis by ABO gene-encoded glycosyltransferases.ABO 与 Forssman（FORS）血型系统之间的串扰：ABO 基因编码的糖基转移酶合成 FORS1 抗原。
Sci Rep. 2017 Jan 30;7:41632. doi: 10.1038/srep41632.
5
Postoperative change of anti-Thomsen-Friedenreich and Tn IgG level: the follow-up study of gastrointestinal cancer patients.抗-Thomsen-Friedenreich和Tn IgG水平的术后变化：胃肠道癌患者的随访研究
World J Gastroenterol. 2008 Jul 21;14(27):4352-8. doi: 10.3748/wjg.14.4352.
6
Isolation and characterization of a Forssman antigen-binding lectin from velvet bean (Mucuna derringiana) seeds.从藜豆（刺毛黧豆）种子中分离并鉴定一种福斯曼抗原结合凝集素。
Glycoconj J. 1994 Oct;11(5):424-31. doi: 10.1007/BF00731278.
7
Autoantibodies against Forssman glycolipids in Graves' disease and Hashimoto's thyroiditis.格雷夫斯病和桥本甲状腺炎中针对福斯曼糖脂的自身抗体。
Clin Exp Immunol. 1991 Dec;86(3):483-8. doi: 10.1111/j.1365-2249.1991.tb02957.x.