Hügel W, Uekermann U, Franz C, Isselhard W, Schorn B, Hirche H, Lübbing H, Dalichau H
Thoraxchir Vask Chir. 1978 Jun;26(3):201-4. doi: 10.1055/s-0028-1096623.
In 22 mongrel dogs the protective effect on the myocardium of Bretschneider- and Kirsch-Cardioplegia (90 minutes of cardiac arrest) was studied and compared with ischemic arrest (45 minutes at hypothermia of 30 degrees C). Myocardial contractility was evaluated by the following indices of contractility: t--dp/dt max., Krayenbühl-Index of contractility and max. Vce. Depression of contractility of 40 % was observed after ischemic arrest and Kirsch-Cardioplegia, whereas in Bretschneider-Cardioplegia depression was only 7 %. Forty-five minutes after reperfusion contractility had returned to normal in the last group. It is concluded that Bretschneider-Cardioplegia results in little reduction of postischemic contractility, and has a good protective effect on the myocardium.
在22只杂种犬中,研究了布雷施奈德式和基尔希式心脏停搏液(心脏停搏90分钟)对心肌的保护作用,并与缺血性停搏(30℃低温下45分钟)进行了比较。通过以下收缩性指标评估心肌收缩性:t-dp/dt max.、克雷延比尔收缩性指数和最大Vce。缺血性停搏和基尔希式心脏停搏液后观察到收缩性降低40%,而布雷施奈德式心脏停搏液的降低仅为7%。再灌注45分钟后,最后一组的收缩性恢复正常。得出的结论是,布雷施奈德式心脏停搏液导致缺血后收缩性降低很少,对心肌有良好的保护作用。