Genest H, Guidoin R, Plante R, Gosselin C, Blais P, Robert G, Laroche B, Marois M, Clavel F, King M
J Urol (Paris). 1982;88(6):337-43.
Two juvenile size silicone testicular prostheses were analyzed following replacement by adult size devices after 72 and 99 months in situ. Scanning electron microscopy and electron microprobe studies were carried out on the explanted silicone prostheses and their attached tissue capsules. The material at the surface of the prostheses gave no evidence of biodeterioration. However, localized sites of calcification were observed. The adjacent tissue capsule consisted of two distinct concentric layers with different morphologies; the one adjacent to the prosthesis consisted of dense arrays of collagen fibres oriented parallel to the silicone surface and extending outward to a thickness of 100-120 microns. The outer layer was less dense, more disordered and was uneven in thickness. It contained numerous discrete particles of silicon-rich material. Technical and clinical implications of these results are discussed.
在原位植入72个月和99个月后,用成人尺寸的装置替换了两个青少年尺寸的硅橡胶睾丸假体,并对其进行了分析。对取出的硅橡胶假体及其附着的组织包膜进行了扫描电子显微镜和电子微探针研究。假体表面的材料没有生物降解的迹象。然而,观察到了局部钙化部位。相邻的组织包膜由两个形态不同的明显同心层组成;与假体相邻的一层由平行于硅橡胶表面排列并向外延伸至100-120微米厚度的致密胶原纤维阵列组成。外层密度较小,更无序,厚度不均匀。它含有许多离散的富硅材料颗粒。讨论了这些结果的技术和临床意义。