大肠杆菌噬菌体186的遗传学研究。II. 与噬菌体复制和宿主细胞裂解相关的基因。
Genetic studies of coliphage 186. II. Genes associated with phage replication and host cell lysis.
作者信息
Hocking S M, Egan J B
出版信息
J Virol. 1982 Dec;44(3):1068-71. doi: 10.1128/JVI.44.3.1068-1071.1982.
Abstract
DNA synthesis in coliphage 186-infected cells was investigated. Phage 186 appeared to inhibit host DNA synthesis early in infection. The subsequent synthesis of phage 186 DNA was dependent on the product of 186 gene A. The product of gene B controlled both the production of late 186 proteins and the cessation of 186 DNA synthesis, and the products of genes O and P had no influence on 186 DNA synthesis. The product of gene P controlled host cell lysis, and the product of gene O may have some regulatory function.
摘要
对大肠杆菌噬菌体186感染的细胞中的DNA合成进行了研究。噬菌体186在感染初期似乎会抑制宿主DNA合成。随后噬菌体186 DNA的合成依赖于186基因A的产物。基因B的产物控制着186晚期蛋白的产生以及186 DNA合成的停止，而基因O和P的产物对186 DNA合成没有影响。基因P的产物控制宿主细胞裂解，基因O的产物可能具有一些调节功能。
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