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肾脏灌注与保存

Kidney perfusion and preservation.

作者信息

Scott D F

出版信息

Med J Aust. 1982 Oct 30;2(9):419-21. doi: 10.5694/j.1326-5377.1982.tb132503.x.

Abstract

Kidney preservation, often for periods in excess of 24 hours, is currently required to allow tissue matching and preparation of the recipient before cadaveric renal transplantation. Both flushing with complex electrolyte solutions and storage in ice saline slush, and hypothermic perfusion are satisfactory techniques. In half of the recipients, despite agonal damage in the donor and the progressive metabolic disturbance during hypothermic storage, the kidneys function immediately after transplantation. In the remaining half, kidneys function after a period of one to three weeks of acute tubular necrosis.

摘要

目前,在尸体肾移植前,需要进行肾脏保存,保存时间通常超过24小时,以便进行组织配型和受体准备。用复合电解质溶液冲洗并储存在冰盐水中,以及低温灌注都是令人满意的技术。在一半的受者中,尽管供体存在濒死损伤以及低温保存期间进行性代谢紊乱,但肾脏在移植后立即发挥功能。在其余一半受者中,肾脏在经历一至三周的急性肾小管坏死期后才发挥功能。

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