Gross V, Flemming B, Roloff D, Joschko K, Oddoy A
Z Gesamte Inn Med. 1982 Sep 15;37(18):601-4.
In pregnant women with physiological hyperinsulinism and in a control group with lower peripheral insulin concentrations after glucose load was investigated, whether differences in the peripheral insulin content involve different relations between the KG-value and the sodium concentration of the erythrocytes. Despite the differences in the peripheral insulin content during the intravenous glucose tolerance test negative correlations between the KG-value and the sodium concentration of the erythrocytes were found in the groups investigated. From this was concluded that these correlations are not based on changes of the peripheral insulin level, as they were established in the present examinations. A conception was presented issuing from the fact that the negative correlation between the KG-value and the sodium concentration is based on properties of the cell membrane which influence the intracellular sodium concentration as well as the effect of insulin in the cell.
对葡萄糖负荷后生理高胰岛素血症的孕妇及外周胰岛素浓度较低的对照组进行研究,观察外周胰岛素含量的差异是否涉及红细胞的KG值与钠浓度之间的不同关系。尽管静脉葡萄糖耐量试验期间外周胰岛素含量存在差异,但在所研究的组中发现红细胞的KG值与钠浓度之间呈负相关。由此得出结论,这些相关性并非基于外周胰岛素水平的变化,因为它们是在当前检查中确定的。基于KG值与钠浓度之间的负相关是基于影响细胞内钠浓度的细胞膜特性以及胰岛素在细胞中的作用这一事实,提出了一种概念。