Leithner C, Sinzinger H, Schwarz M, Pohanka E, Syre G
Clin Nephrol. 1982 Dec;18(6):311-3.
Increased deposition of 111In-oxine labelled autologous platelets in chronically rejected kidney transplants was demonstrated using a gamma-camera and by measurement of a platelet uptake index (PUI). In this group of patients the PUI correlated indirectly with the platelet half-life and was statistically different from the PUI found in stable transplant patients who acted as controls. It is therefore suggested that platelets may play a key role in chronic rejection by the release of a mitogenic factor which promotes the development of obliterative arterial lesions in the transplant.
利用γ相机并通过测量血小板摄取指数（PUI），证实了铟-111 奥克辛标记的自体血小板在慢性排斥肾移植中的沉积增加。在这组患者中，PUI 与血小板半衰期呈间接相关，且与作为对照的稳定移植患者的 PUI 在统计学上存在差异。因此，提示血小板可能通过释放促有丝分裂因子在慢性排斥中起关键作用，该因子促进移植中闭塞性动脉病变的发展。
