通过同步放射成像和氦稀释法估算肺组织体积。
Lung tissue volume estimated by simultaneous radiographic and helium dilution methods.
作者信息
Armstrong J D, Gluck E H, Crapo R O, Jones H A, Hughes J M
出版信息
Thorax. 1982 Sep;37(9):676-9. doi: 10.1136/thx.37.9.676.
Abstract
The pulmonary total tissue volume (blood, extravascular water, and dry tissue volume) was measured by finding the difference between the radiographic displacement volume of the thorax (RDVT) and the lung gas volume. Simultaneous determinations of RDVT and gas volume were made in 10 healthy subjects sitting upright. RDVT was determined from posteroanterior and lateral chest radiographs, a computerised modification of the Barnhard method being used; and gas volume was measured by helium dilution with each radiographic exposure. At functional residual capacity pulmonary total tissue volume was 843 +/- 110 ml (1 SD). The density of the lung (ml tissue per ml tissue and gas) was 0.19 +/- 0.03 (1 SD). This method, different in principle from indicator-dilution and acetylene rebreathing studies, provides measurements of total tissue volume.
摘要
通过计算胸廓的X线移位容积（RDVT）与肺气体容积之间的差值来测量肺的总组织容积（血液、血管外水分和干组织容积）。对10名直立位健康受试者同时测定RDVT和气体容积。RDVT通过后前位和侧位胸部X线片测定，采用Barnhard方法的计算机化改良方法；每次X线曝光时通过氦稀释法测量气体容积。在功能残气量时，肺总组织容积为843±110 ml（标准差为1）。肺的密度（每毫升组织和气体中的组织毫升数）为0.19±0.03（标准差为1）。该方法在原理上不同于指示剂稀释法和乙炔再呼吸研究，可提供总组织容积的测量值。
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