Gopinathan V P, Subramanian A R
Med J Aust. 1982;2(12):568-72.
Records of 560 male patients with Plasmodium vivax and P. falciparum infection, who were admitted to a military hospital in the northeastern sector of India during the period from June, 1978, to June, 1980, have been analysed to establish the prevalence of pernicious syndromes. One hundred and seventy-eight patients (31.8%) had P. vivax malaria, 309 (55.1%) had P. falciparum malaria, and the remaining 73 (13.1%) were found to have mixed infection (P. vivax and P. falciparum). Pernicious syndromes with single or multiple organ involvement, of which cerebral and haemopoietic complications were the most common (29.4% and 47.1% respectively), were seen in 68 patients. While the fewest complications occurred with P. vivax malaria (in only 2.3% of cases), complications were present in 27.4% of cases of mixed infection, and in 14.2% of cases of pure P. falciparum malaria. Awareness of changing and atypical manifestations and early recognition with timely institution of specific therapy determine the chances of recovery from this preventable disease.
对1978年6月至1980年6月期间收治于印度东北部一家军队医院的560例间日疟原虫和恶性疟原虫感染男性患者的记录进行了分析，以确定凶险综合征的患病率。178例患者（31.8%）患有间日疟，309例（55.1%）患有恶性疟，其余73例（13.1%）为混合感染（间日疟原虫和恶性疟原虫）。68例患者出现了累及单个或多个器官的凶险综合征，其中脑和血液系统并发症最为常见（分别为29.4%和47.1%）。间日疟患者出现的并发症最少（仅2.3%的病例），混合感染病例中有27.4%出现并发症，单纯恶性疟病例中有14.2%出现并发症。认识到症状的变化和不典型表现并早期识别，及时进行特异性治疗，决定了从这种可预防疾病中康复的机会。
