Broekhuyse R M, van de Putte L B, Pinckers A J, Brinkman C J
Acta Ophthalmol (Copenh). 1982 Oct;60(5):815-20. doi: 10.1111/j.1755-3768.1982.tb06744.x.
Fourteen patients with rheumatoid arthritis were tested for the presence of cell-mediated immune reactivity to various ocular antigens by means of the leucocyte migration inhibition test. A significant difference in leucocyte migration was found between patients and healthy controls after incubation of their cells with purified rhodopsin, uveal pigment granules or soluble uveal antigens, but not with rod outer segments or soluble retinal antigens. Some indications have been obtained that the sensitization to rhodopsin in fact originates from a sensitization to connective tissue structural glycoproteins.
通过白细胞移动抑制试验，对14例类风湿性关节炎患者进行了针对各种眼部抗原的细胞介导免疫反应性检测。在用纯化的视紫红质、葡萄膜色素颗粒或可溶性葡萄膜抗原孵育细胞后，患者与健康对照之间发现白细胞移动存在显著差异，但与视杆细胞外段或可溶性视网膜抗原孵育时未发现差异。已获得一些迹象表明，对视紫红质的致敏实际上源于对结缔组织结构糖蛋白的致敏。
