Chandran P K, First M R, Weiss M A, Hess E V, Alexander J W, Pazmino P, Pollak V E
Am J Nephrol. 1982;2(6):325-9. doi: 10.1159/000166672.
Wegener's granulomatosis was diagnosed in a 42-year-old female 16 years ago. From the outset there was upper respiratory, pulmonary, and renal involvement. Over the years she received varying combinations of glucocorticoids and azathioprine. Renal function deteriorated, and she was treated by hemodialysis and living related donor transplantation 9 and 10 years, respectively, after the onset of the disease. 3 months prior to transplantation, the patient had a right pneumonectomy for bronchial stenosis, bronchiectasis and repeated sepsis. 5 years' posttransplantation, she is well and has no signs of activity of original disease.
16年前，一名42岁女性被诊断为韦格纳肉芽肿。从一开始就有上呼吸道、肺部和肾脏受累。多年来，她接受了糖皮质激素和硫唑嘌呤的不同组合治疗。肾功能恶化，在疾病发作后9年和10年，她分别接受了血液透析和活体亲属供肾移植治疗。移植前3个月，患者因支气管狭窄、支气管扩张和反复败血症接受了右肺切除术。移植后5年，她情况良好，没有原发病活动的迹象。
