Nikonov A A
Vopr Onkol. 1978;24(7):62-8.
The work is concerned with the study of gastric tumors showing histological similarity with carcinoids, but differing from them by morphological and clinical signs of malignancy. A conclusion is made on the carcinoid nature of the neoplasms under consideration, the following evidences being presented: 1) despite some differences the tumors correspond histologically to classical carcinoids; 2) as in common carcinoids, argyrophil or argentaffine granules may be revealed in tumor cells; 3) the occurrences of tumors is related with a peculiar neoplastic transformation of glandular epithelium of the stomach resembling carcinoid rather than cancerous one. Not excluding the possibiltiy of their origin from common carcinoids, the author believes that they are likely to be primary malignant tumors.
这项工作致力于研究与类癌在组织学上相似,但在恶性形态学和临床体征上与之不同的胃肿瘤。得出了关于所研究肿瘤类癌性质的结论,并给出了以下证据:1)尽管存在一些差异,但这些肿瘤在组织学上与经典类癌相符;2)与常见类癌一样,肿瘤细胞中可发现嗜银或亲银颗粒;3)肿瘤的发生与胃腺上皮特殊的类癌样而非癌样肿瘤转化有关。作者不排除它们起源于常见类癌的可能性,但认为它们很可能是原发性恶性肿瘤。